Sirtuins are a family of 7 proteins that play a role in cellular health and are also known as the longevity genes. Our body makes these sirtuins as defensive enzymes that keeps our cells healthy and young through DNA repair. They play an important role in the regulation of cellular homeostasis, in particular metabolism, inflammation, oxidative stress and senescence, As we age, the sirtuin’s activity decreases, contributing to the development of various diseases such as chronic diabetes, heart disease, Alzheimer’s.

Sirtuins can only function in the presence of NAD+. NAD+ is vital to cellular metabolism and hundreds of other biological processes and when you raise the levels of NAD, the sirtuins get activated which helps increase your health and life span. When there is a break in the DNA within the cell, the sirtuin’s job is to repair the damage and also perform various other functions within the cell to make sure they function properly.

Sirtuins need NAD+ to fuel them in order to help prevent aging and fight diseases in our body. These include:

Supplementing with NAD+ precursoes such as EpicG’s NMN Boost+ helps to activate Sirtuins and delay the aging process.